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Testing For B12 Deficiency: There are several different ways you can test for a functional B12 deficiency

Claiming oral equivalence to injection on the basis of gastric stability alone skips several critical steps in the pharmacokinetic argument

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Extraintestinal manifestations can affect any organ system, and while in many cases these symptoms are believed to be a result of the underlying intestinal inflammation, some extraintestinal manifestations are independent of the luminal disease course

This multi-axis neuroendocrine regulatory profile positions DSIP as a broad hypothalamic-pituitary axis modulator, not merely a sleep-specific peptide, and makes it a research tool for studying the neuroendocrine consequences of altered sleep homeostasis and circadian rhythm disruption